HIV Target gene Detail Information

> DUSP11 Gene Search Result

Gene Information

Gene Name	DUSP11
Gene ID	8446
Gene Full Name	dual specificity phosphatase 11
Gene Alias	PIR1
Transcripts	ENSG00000144048
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli fibrillar center;Nucleoplasm;Cytokinetic bridge;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O75319
HGNC ID	HGNC:3066
VEGA ID	OTTHUMG00000129816
OMIM ID	603092
String ID	9606.ENSP00000272444
PharmGKB ID	PA27521

Target gene [DUSP11] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4013657	chr2	1	2		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DUSP11 expression and immune infiltrating cell level correlation result in HIV+ samples
DUSP11 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DUSP11 expression and immune infiltrating cell level correlation result in HIV+ samples
DUSP11 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).