HBV Target gene Detail Information

> DTNA Gene Search Result


Gene Information
Gene Name DTNA
Gene ID 1837
Gene Full Name dystrobrevin alpha
Gene Alias DTN; DRP3; DTN-A; LVNC1; D18S892E
Transcripts ENSG00000134769
Virus HBV
Gene Type protein coding
HPA Location Info Cell Junctions;Intermediate filaments;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q9Y4J8
HGNC ID HGNC:3057
VEGA ID OTTHUMG00000132309
OMIM ID 601239
String ID 9606.ENSP00000470152
PharmGKB ID PA27510
Target gene [DTNA] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1011170 chr18 7 2 1 10 View
1016025 chr18 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DTNA expression and immune infiltrating cell level correlation result in HBV+ samples
DTNA expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).