HTLV1 Target gene Detail Information

> DTHD1 Gene Search Result

Gene Information

Gene Name	DTHD1
Gene ID	401124
Gene Full Name	death domain containing 1
Transcripts	ENSG00000197057
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q6ZMT9
HGNC ID	HGNC:37261
VEGA ID	OTTHUMG00000160371
OMIM ID	616979
String ID	9606.ENSP00000401597
PharmGKB ID	PA165663634

Target gene [DTHD1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6001229	chr4	453	22	49	524	View
6024641	chr4	2		1	3	View
6032218	chr4				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of DTHD1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
DTHD1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).