HBV Target gene Detail Information

> DSTYK Gene Search Result

Gene Information

Gene Name	DSTYK
Gene ID	25778
Gene Full Name	dual serine/threonine and tyrosine protein kinase
Gene Alias	RIP5; RIPK5; SPG23; CAKUT1; DustyPK; HDCMD38P
Transcripts	ENSG00000133059
Virus	HBV
Gene Type	protein coding
HPA Location Info	Intermediate filaments;Nuclear speckles;Cytosol;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q6XUX3
HGNC ID	HGNC:29043
VEGA ID	OTTHUMG00000037102
OMIM ID	612666
String ID	9606.ENSP00000356130
PharmGKB ID	PA164718861

Target gene [DSTYK] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001779	chr1	412	73		485	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of DSTYK expression and immune infiltrating cell level correlation result in HBV+ samples
DSTYK expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).