HIV Target gene Detail Information

> DSTN Gene Search Result

Gene Information

Gene Name	DSTN
Gene ID	11034
Gene Full Name	destrin, actin depolymerizing factor
Gene Alias	ADF; ACTDP; HEL32; bA462D18.2
Transcripts	ENSG00000125868
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	P60981
HGNC ID	HGNC:15750
VEGA ID	OTTHUMG00000031947
OMIM ID	609114
String ID	9606.ENSP00000246069
Drugbank ID	BE0004166
PharmGKB ID	PA27509

Target gene [DSTN] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002061	chr20	75	8	31	114	View
4002062	chr20	75	8	31	114	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DSTN expression and immune infiltrating cell level correlation result in HIV+ samples
DSTN expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DSTN expression and immune infiltrating cell level correlation result in HIV+ samples
DSTN expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).