HTLV1 Target gene Detail Information

> DSP Gene Search Result

Gene Information

Gene Name	DSP
Gene ID	1832
Gene Full Name	desmoplakin
Gene Alias	DP; DCWHKTA
Transcripts	ENSG00000096696
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cell Junctions;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	P15924
HGNC ID	HGNC:3052
VEGA ID	OTTHUMG00000014212
OMIM ID	125647
String ID	9606.ENSP00000369129
Drugbank ID	BE0008999
PharmGKB ID	PA27505

Target gene [DSP] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6004887	chr6	19	54	28	101	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of DSP expression and immune infiltrating cell level correlation result in HTLV1+ samples
DSP expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of DSP expression and immune infiltrating cell level correlation result in HTLV1+ samples
DSP expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of DSP expression and immune infiltrating cell level correlation result in HTLV1+ samples
DSP expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).