HIV Target gene Detail Information

> DSN1 Gene Search Result

Gene Information

Gene Name	DSN1
Gene ID	79980
Gene Full Name	DSN1 homolog, MIS12 kinetochore complex component
Gene Alias	KNL3; MIS13; hKNL-3; C20orf172; dJ469A13.2
Transcripts	ENSG00000149636
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;Kinetochore;Nuclear bodies;Nucleoli fibrillar center;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9H410
HGNC ID	HGNC:16165
VEGA ID	OTTHUMG00000032396
OMIM ID	609175
String ID	9606.ENSP00000389810
PharmGKB ID	PA162384106

Target gene [DSN1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006084	chr20	6	21		27	View
4007853	chr20	13	4		17	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DSN1 expression and immune infiltrating cell level correlation result in HIV+ samples
DSN1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DSN1 expression and immune infiltrating cell level correlation result in HIV+ samples
DSN1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).