HIV Target gene Detail Information

> DSG2 Gene Search Result

Gene Information

Gene Name	DSG2
Gene ID	1829
Gene Full Name	desmoglein 2
Gene Alias	HDGC; CDHF5
Transcripts	ENSG00000046604
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cell Junctions;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q14126
HGNC ID	HGNC:3049
VEGA ID	OTTHUMG00000179649
OMIM ID	125671
String ID	9606.ENSP00000261590
PharmGKB ID	PA27502

Target gene [DSG2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002603	chr18	10	67	10	87	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DSG2 expression and immune infiltrating cell level correlation result in HIV+ samples
DSG2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).