HIV Target gene Detail Information

> DRAM2 Gene Search Result

Gene Information

Gene Name	DRAM2
Gene ID	128338
Gene Full Name	DNA damage regulated autophagy modulator 2
Gene Alias	CORD21; PRO180; TMEM77; WWFQ154
Transcripts	ENSG00000156171
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q6UX65
HGNC ID	HGNC:28769
VEGA ID	OTTHUMG00000011911
OMIM ID	613360
String ID	9606.ENSP00000286692
PharmGKB ID	PA165751270

Target gene [DRAM2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001613	chr1	146			146	View
4003148	chr1	68			68	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DRAM2 expression and immune infiltrating cell level correlation result in HIV+ samples
DRAM2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).