HIV Target gene Detail Information

> DR1 Gene Search Result

Gene Information

Gene Name	DR1
Gene ID	1810
Gene Full Name	down-regulator of transcription 1
Gene Alias	NC2; NC2B; NCB2; NC2-BETA
Transcripts	ENSG00000117505
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q01658
HGNC ID	HGNC:3017
VEGA ID	OTTHUMG00000010862
OMIM ID	601482
String ID	9606.ENSP00000359295
PharmGKB ID	PA27475

Target gene [DR1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004070	chr1	37	13		50	View
4004260	chr1	34	13		47	View
4004668	chr1	30	11		41	View
4004927	chr1	30	8		38	View
4004928	chr1	30	8		38	View
4006544	chr6	13	11		24	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DR1 expression and immune infiltrating cell level correlation result in HIV+ samples
DR1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DR1 expression and immune infiltrating cell level correlation result in HIV+ samples
DR1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).