HTLV1 Target gene Detail Information

> DPYSL2 Gene Search Result

Gene Information

Gene Name	DPYSL2
Gene ID	1808
Gene Full Name	dihydropyrimidinase like 2
Gene Alias	DRP2; N2A3; CRMP2; DRP-2; ULIP2; CRMP-2; DHPRP2; ULIP-2
Transcripts	ENSG00000092964
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q16555
HGNC ID	HGNC:3014
VEGA ID	OTTHUMG00000099439
OMIM ID	602463
String ID	9606.ENSP00000309539
Drugbank ID	BE0005853; BE0005806
PharmGKB ID	PA27472

Target gene [DPYSL2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6004097	chr8	31	21	77	129	View
6006775	chr8	62	1		63	View
6014163	chr8	9	2	6	17	View
6016057	chr8	12	1		13	View
6024998	chr8		3		3	View
6032778	chr8				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of DPYSL2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
DPYSL2 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of DPYSL2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
DPYSL2 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of DPYSL2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
DPYSL2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).