HBV Target gene Detail Information

> DOK6 Gene Search Result

Gene Information

Gene Name	DOK6
Gene ID	220164
Gene Full Name	docking protein 6
Gene Alias	DOK5L; HsT3226
Transcripts	ENSG00000206052
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Focal adhesion sites;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q6PKX4
HGNC ID	HGNC:28301
VEGA ID	OTTHUMG00000178688
OMIM ID	611402
String ID	9606.ENSP00000372160
PharmGKB ID	PA134866995

Target gene [DOK6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001414	chr18	74	443	245	762	View
1002052	chr18	28	244	89	361	View
1404502	chr18	16			16	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of DOK6 expression and immune infiltrating cell level correlation result in HBV+ samples
DOK6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).