HBV Target gene Detail Information

> DOK6 Gene Search Result


Gene Information
Gene Name DOK6
Gene ID 220164
Gene Full Name docking protein 6
Gene Alias DOK5L; HsT3226
Transcripts ENSG00000206052
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Focal adhesion sites;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q6PKX4
HGNC ID HGNC:28301
VEGA ID OTTHUMG00000178688
OMIM ID 611402
String ID 9606.ENSP00000372160
PharmGKB ID PA134866995
Target gene [DOK6] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001414 chr18 74 443 245 762 View
1002052 chr18 28 244 89 361 View
1404502 chr18 16 16 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DOK6 expression and immune infiltrating cell level correlation result in HBV+ samples
DOK6 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).