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HBV Target gene Detail Information

> DOK5 Gene Search Result


Gene Information
Gene Name DOK5
Gene ID 55816
Gene Full Name docking protein 5
Gene Alias IRS6; IRS-6; C20orf180
Transcripts ENSG00000101134
Virus HBV
Gene Type protein coding
HPA Location Info Focal adhesion sites;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9P104
HGNC ID HGNC:16173
VEGA ID OTTHUMG00000032778
OMIM ID 608334
String ID 9606.ENSP00000262593
PharmGKB ID PA25724
Target gene [DOK5] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005839 chr20 34 12 1 47 View
1005881 chr20 33 12 1 46 View
1005882 chr20 33 12 1 46 View
1005883 chr20 33 12 1 46 View
1005884 chr20 33 12 1 46 View
1005885 chr20 33 12 1 46 View
1005906 chr20 33 12 1 46 View
1005926 chr20 33 12 1 46 View
1009952 chr20 2 6 6 14 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DOK5 expression and immune infiltrating cell level correlation result in HBV+ samples
DOK5 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).