HIV Target gene Detail Information

> DOCK7 Gene Search Result

Gene Information

Gene Name	DOCK7
Gene ID	85440
Gene Full Name	dedicator of cytokinesis 7
Gene Alias	ZIR2; EIEE23
Transcripts	ENSG00000116641
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q96N67
HGNC ID	HGNC:19190
VEGA ID	OTTHUMG00000013131
OMIM ID	615730
String ID	9606.ENSP00000251157
PharmGKB ID	PA134872825

Target gene [DOCK7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009291	chr1	12			12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DOCK7 expression and immune infiltrating cell level correlation result in HIV+ samples
DOCK7 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DOCK7 expression and immune infiltrating cell level correlation result in HIV+ samples
DOCK7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).