HBV Target gene Detail Information

> DOCK4 Gene Search Result

Gene Information

Gene Name	DOCK4
Gene ID	9732
Gene Full Name	dedicator of cytokinesis 4
Transcripts	ENSG00000128512
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoli;Plasma membrane;Cytosol;Golgi apparatus;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q8N1I0
HGNC ID	HGNC:19192
VEGA ID	OTTHUMG00000155077
OMIM ID	607679
String ID	9606.ENSP00000404179
PharmGKB ID	PA134939318

Target gene [DOCK4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009491	chr7	15			15	View
1018429	chr7				0	View
1401891	chr7	15			15	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of DOCK4 expression and immune infiltrating cell level correlation result in HBV+ samples
DOCK4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).