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HBV Target gene Detail Information

> DNPEP Gene Search Result


Gene Information
Gene Name DNPEP
Gene ID 23549
Gene Full Name aspartyl aminopeptidase
Gene Alias DAP; ASPEP
Transcripts ENSG00000123992
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q9ULA0
HGNC ID HGNC:2981
VEGA ID OTTHUMG00000058919
OMIM ID 611367
String ID 9606.ENSP00000273075
Drugbank ID BE0002277
PharmGKB ID PA27448
Target gene [DNPEP] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000417 chr2 1133 869 420 2422 View
1000834 chr2 128 155 1088 1371 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of DNPEP expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
DNPEP expression: Low -> High
Lollipop of DNPEP expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of DNPEP expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DNPEP expression and immune infiltrating cell level correlation result in HBV+ samples
DNPEP expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).