HIV Target gene Detail Information

> DNM2 Gene Search Result

Gene Information

Gene Name	DNM2
Gene ID	1785
Gene Full Name	dynamin 2
Gene Alias	DYN2; CMT2M; DYNII; LCCS5; CMTDI1; CMTDIB; DI-CMTB
Transcripts	ENSG00000079805
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Golgi apparatus;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters
Uniport_ID	P50570
HGNC ID	HGNC:2974
VEGA ID	OTTHUMG00000180694
OMIM ID	602378
String ID	9606.ENSP00000373905
PharmGKB ID	PA27442

Target gene [DNM2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001436	chr19	154	11		165	View
4003349	chr19	46	15	2	63	View
4003538	chr19	56	3		59	View
4004266	chr19	19	4	24	47	View
4011462	chr19	6	1		7	View
4013104	chr19	4			4	View
4013526	chr19	1	2		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DNM2 expression and immune infiltrating cell level correlation result in HIV+ samples
DNM2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DNM2 expression and immune infiltrating cell level correlation result in HIV+ samples
DNM2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).