HIV Target gene Detail Information

> DNM1L Gene Search Result

Gene Information

Gene Name	DNM1L
Gene ID	10059
Gene Full Name	dynamin 1 like
Gene Alias	DLP1; DRP1; DVLP; EMPF; OPA5; EMPF1; DYMPLE; HDYNIV
Transcripts	ENSG00000087470
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Vesicles;
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	O00429
HGNC ID	HGNC:2973
VEGA ID	OTTHUMG00000169451
OMIM ID	603850
String ID	9606.ENSP00000449089
PharmGKB ID	PA27441

Target gene [DNM1L] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002947	chr12	67	7		74	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DNM1L expression and immune infiltrating cell level correlation result in HIV+ samples
DNM1L expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DNM1L expression and immune infiltrating cell level correlation result in HIV+ samples
DNM1L expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).