HBV Target gene Detail Information

> DNAJC6 Gene Search Result


Gene Information
Gene Name DNAJC6
Gene ID 9829
Gene Full Name DnaJ heat shock protein family (Hsp40) member C6
Gene Alias DJC6; PARK19
Transcripts ENSG00000116675
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;Plasma membrane;
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID O75061
HGNC ID HGNC:15469
VEGA ID OTTHUMG00000009066
OMIM ID 608375
String ID 9606.ENSP00000360108
PharmGKB ID PA27423
Target gene [DNAJC6] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005102 chr1 23 34 4 61 View
1006160 chr1 21 19 2 42 View
1012685 chr1 6 6 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DNAJC6 expression and immune infiltrating cell level correlation result in HBV+ samples
DNAJC6 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).