HIV Target gene Detail Information

> DNAJC5 Gene Search Result

Gene Information

Gene Name	DNAJC5
Gene ID	80331
Gene Full Name	DnaJ heat shock protein family (Hsp40) member C5
Gene Alias	CSP; NCL; CLN4; CLN4B; DNAJC5A; mir-941-2; mir-941-3; mir-941-4; mir-941-5
Transcripts	ENSG00000101152
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Plasma membrane;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted membrane proteins
Uniport_ID	Q9H3Z4
HGNC ID	HGNC:16235
VEGA ID	OTTHUMG00000033007
OMIM ID	611203
String ID	9606.ENSP00000354111
PharmGKB ID	PA27422

Target gene [DNAJC5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000960	chr20	21	185	33	239	View
4001825	chr20	93	9	27	129	View
4003716	chr20	24	27	5	56	View
4004869	chr20	36	2		38	View
4005965	chr20	7	9	12	28	View
4016005	chr20				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DNAJC5 expression and immune infiltrating cell level correlation result in HIV+ samples
DNAJC5 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DNAJC5 expression and immune infiltrating cell level correlation result in HIV+ samples
DNAJC5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).