HBV Target gene Detail Information

> DNAJC1 Gene Search Result


Gene Information
Gene Name DNAJC1
Gene ID 64215
Gene Full Name DnaJ heat shock protein family (Hsp40) member C1
Gene Alias HTJ1; MTJ1; ERdj1; DNAJL1
Transcripts ENSG00000136770
Virus HBV
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins, Transcription factors
Uniport_ID Q96KC8
HGNC ID HGNC:20090
VEGA ID OTTHUMG00000017800
OMIM ID 611207
String ID 9606.ENSP00000366179
PharmGKB ID PA128394706
Target gene [DNAJC1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005435 chr10 17 30 7 54 View
1009887 chr10 12 2 14 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DNAJC1 expression and immune infiltrating cell level correlation result in HBV+ samples
DNAJC1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).