HBV Target gene Detail Information

> DNAJB1 Gene Search Result


Gene Information
Gene Name DNAJB1
Gene ID 3337
Gene Full Name DnaJ heat shock protein family (Hsp40) member B1
Gene Alias Hdj1; Sis1; HSPF1; Hsp40; RSPH16B
Transcripts ENSG00000132002
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID P25685
HGNC ID HGNC:5270
VEGA ID OTTHUMG00000183289
OMIM ID 604572
String ID 9606.ENSP00000254322
PharmGKB ID PA27412
Target gene [DNAJB1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003506 chr19 124 5 129 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DNAJB1 expression and immune infiltrating cell level correlation result in HBV+ samples
DNAJB1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).