HIV Target gene Detail Information

> DNAJA3 Gene Search Result

Gene Information

Gene Name	DNAJA3
Gene ID	9093
Gene Full Name	DnaJ heat shock protein family (Hsp40) member A3
Gene Alias	TID1; HCA57; hTID-1
Transcripts	ENSG00000276726
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q96EY1
HGNC ID	HGNC:11808
VEGA ID	OTTHUMG00000190863
OMIM ID	608382
String ID	9606.ENSP00000262375
PharmGKB ID	PA27410

Target gene [DNAJA3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002784	chr16	63	16	1	80	View
4007442	chr16	10	8	1	19	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DNAJA3 expression and immune infiltrating cell level correlation result in HIV+ samples
DNAJA3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DNAJA3 expression and immune infiltrating cell level correlation result in HIV+ samples
DNAJA3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).