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HPV Target gene Detail Information

> DNAH12 Gene Search Result


Gene Information
Gene Name DNAH12
Gene ID 201625
Gene Full Name dynein axonemal heavy chain 12
Gene Alias DHC3; DLP3; HL19; DLP12; DNHD2; HDHC3; HL-19; DNAH7L; DNAHC3; DNAH12L; DNAHC12
Transcripts ENSG00000174844
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Cancer-related genes, Predicted intracellular proteins
Uniport_ID Q6ZR08
HGNC ID HGNC:2943
VEGA ID OTTHUMG00000158598
OMIM ID 603340
String ID 9606.ENSP00000312554
PharmGKB ID PA27397
Target gene [DNAH12] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5002537 chr3 6 4 10 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of DNAH12 expression and immune infiltrating cell level correlation result in HPV+ samples
DNAH12 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of DNAH12 expression and immune infiltrating cell level correlation result in HPV+ samples
DNAH12 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of DNAH12 expression and immune infiltrating cell level correlation result in HPV+ samples
DNAH12 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of DNAH12 expression and immune infiltrating cell level correlation result in HPV+ samples
DNAH12 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of DNAH12 expression and immune infiltrating cell level correlation result in HPV+ samples
DNAH12 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).