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HBV Target gene Detail Information

> DMXL2 Gene Search Result


Gene Information
Gene Name DMXL2
Gene ID 23312
Gene Full Name Dmx like 2
Gene Alias RC3; PEPNS; DFNA71
Transcripts ENSG00000104093
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q8TDJ6
HGNC ID HGNC:2938
VEGA ID OTTHUMG00000131749
OMIM ID 612186
String ID 9606.ENSP00000441858
PharmGKB ID PA27392
Target gene [DMXL2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007580 chr15 25 1 26 View
1014113 chr15 3 1 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of DMXL2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
DMXL2 expression: Low -> High
Lollipop of DMXL2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of DMXL2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DMXL2 expression and immune infiltrating cell level correlation result in HBV+ samples
DMXL2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).