HBV Target gene Detail Information

> DMC1 Gene Search Result


Gene Information
Gene Name DMC1
Gene ID 11144
Gene Full Name DNA meiotic recombinase 1
Gene Alias DMC1H; LIM15; dJ199H16.1
Transcripts ENSG00000100206
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q14565
HGNC ID HGNC:2927
VEGA ID OTTHUMG00000151088
OMIM ID 602721
String ID 9606.ENSP00000216024
Drugbank ID BE0004447
PharmGKB ID PA27377
Target gene [DMC1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1010768 chr22 11 11 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DMC1 expression and immune infiltrating cell level correlation result in HBV+ samples
DMC1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).