HIV Target gene Detail Information

> DLG4 Gene Search Result

Gene Information

Gene Name	DLG4
Gene ID	1742
Gene Full Name	discs large MAGUK scaffold protein 4
Gene Alias	PSD95; SAP90; SAP-90
Transcripts	ENSG00000132535
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins, Transporters
Uniport_ID	P78352
HGNC ID	HGNC:2903
VEGA ID	OTTHUMG00000134327
OMIM ID	602887
String ID	9606.ENSP00000382428
Drugbank ID	BE0004524
PharmGKB ID	PA27359

Target gene [DLG4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010795	chr17	7	1		8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DLG4 expression and immune infiltrating cell level correlation result in HIV+ samples
DLG4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).