HBV Target gene Detail Information

> DLG2 Gene Search Result

Gene Information

Gene Name	DLG2
Gene ID	1740
Gene Full Name	discs large MAGUK scaffold protein 2
Gene Alias	PSD93; PSD-93; PPP1R58; chapsyn-110
Transcripts	ENSG00000150672
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q15700
HGNC ID	HGNC:2901
VEGA ID	OTTHUMG00000134309
OMIM ID	603583
String ID	9606.ENSP00000365272
PharmGKB ID	PA164741388

Target gene [DLG2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001601	chr11	503	24	62	589	View
1001602	chr11	503	24	62	589	View
1001620	chr11	495	21	57	573	View
1002475	chr11	251	10	6	267	View
1007154	chr11	10	1	19	30	View
1012661	chr11	6			6	View
1013808	chr11	2	2		4	View
1013969	chr11	4			4	View
1015072	chr11		3		3	View
1016967	chr11		1		1	View
1016968	chr11		1		1	View
1017524	chr11				0	View
1018364	chr11				0	View
1018732	chr11				0	View
1018733	chr11				0	View
1403467	chr11	495	21	57	573	View
1403468	chr11	251	10	6	267	View
1404370	chr11	5	4		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of DLG2 expression and immune infiltrating cell level correlation result in HBV+ samples
DLG2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).