HIV Target gene Detail Information

> DLEU1 Gene Search Result

Gene Information

Gene Name	DLEU1
Gene ID	10301
Gene Alias	BCMS; DLB1; LEU1; LEU2; XTP6; BCMS1; DLEU2; LINC00021; NCRNA00021
Transcripts	ENSG00000176124
Virus	HIV
Gene Type	ncRNA
HPA Location Info
Gene Function	Suppressor gene
HGNC ID	HGNC:13747
VEGA ID	OTTHUMG00000016934
OMIM ID	605765
String ID	9606.ENSP00000367422
lncRNASNP2 ID	NONHSAG013524.2
PharmGKB ID	PA27354

Target gene [DLEU1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005061	chr13	36			36	View
4013427	chr13	1	2		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DLEU1 expression and immune infiltrating cell level correlation result in HIV+ samples
DLEU1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DLEU1 expression and immune infiltrating cell level correlation result in HIV+ samples
DLEU1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).