Home
Virus
Gene
Disease
Dataset
Download
Help
 
HBV Target gene Detail Information

> DLAT Gene Search Result


Gene Information
Gene Name DLAT
Gene ID 1737
Gene Full Name dihydrolipoamide S-acetyltransferase
Gene Alias DLTA; PDCE2; PDC-E2
Transcripts ENSG00000150768
Virus HBV
Gene Type protein coding
HPA Location Info Mitochondria;
HPA Protein Class Info Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID P10515
HGNC ID HGNC:2896
VEGA ID OTTHUMG00000133751
OMIM ID 608770
String ID 9606.ENSP00000280346
Drugbank ID BE0000065
PharmGKB ID PA27350
Target gene [DLAT] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005638 chr11 36 13 1 50 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of DLAT expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
DLAT expression: Low -> High
Lollipop of DLAT expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of DLAT expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DLAT expression and immune infiltrating cell level correlation result in HBV+ samples
DLAT expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).