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HBV Target gene Detail Information

> DISP1 Gene Search Result


Gene Information
Gene Name DISP1
Gene ID 84976
Gene Full Name dispatched RND transporter family member 1
Gene Alias DISPA
Transcripts ENSG00000154309
Virus HBV
Gene Type protein coding
HPA Location Info Nuclear bodies;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins
Uniport_ID Q96F81
HGNC ID HGNC:19711
VEGA ID OTTHUMG00000037893
OMIM ID 607502
String ID 9606.ENSP00000284476
PharmGKB ID PA134938043
Target gene [DISP1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004295 chr1 26 49 11 86 View
1004932 chr1 16 28 22 66 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of DISP1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
DISP1 expression: Low -> High
Lollipop of DISP1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of DISP1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DISP1 expression and immune infiltrating cell level correlation result in HBV+ samples
DISP1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).