HBV Target gene Detail Information

> DIS3L2 Gene Search Result

Gene Information

Gene Name	DIS3L2
Gene ID	129563
Gene Full Name	DIS3 like 3'-5' exoribonuclease 2
Gene Alias	FAM6A; PRLMNS; hDIS3L2
Transcripts	ENSG00000144535
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q8IYB7
HGNC ID	HGNC:28648
VEGA ID	OTTHUMG00000153385
OMIM ID	614184
String ID	9606.ENSP00000315569
PharmGKB ID	PA162383714

Target gene [DIS3L2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007905	chr2	2	19	2	23	View
1010784	chr2	11			11	View
1012670	chr2	5	1		6	View
1403055	chr2	2	19	2	23	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of DIS3L2 expression and immune infiltrating cell level correlation result in HBV+ samples
DIS3L2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).