HBV Target gene Detail Information

> DIRC3 Gene Search Result

Gene Information

Gene Name	DIRC3
Gene ID	729582
Virus	HBV
Gene Type	ncRNA
HPA Protein Class Info	Predicted intracellular proteins
HGNC ID	HGNC:17805
VEGA ID	OTTHUMG00000155287
OMIM ID	608262
String ID	9606.ENSP00000389455
PharmGKB ID	PA134944938

Target gene [DIRC3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001831	chr2	268	99	98	465	View
1003845	chr2	97	7	1	105	View
1013139	chr2	2	3		5	View
1401563	chr2	2	3		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of DIRC3 expression and immune infiltrating cell level correlation result in HBV+ samples
DIRC3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).