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HBV Target gene Detail Information

> DIP2A Gene Search Result


Gene Information
Gene Name DIP2A
Gene ID 23181
Gene Full Name disco interacting protein 2 homolog A
Gene Alias DIP2; C21orf106
Transcripts ENSG00000160305
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q14689
HGNC ID HGNC:17217
VEGA ID OTTHUMG00000090717
OMIM ID 607711
String ID 9606.ENSP00000392066
PharmGKB ID PA134888233
Target gene [DIP2A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007484 chr21 27 27 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of DIP2A expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
DIP2A expression: Low -> High
Lollipop of DIP2A expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of DIP2A expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DIP2A expression and immune infiltrating cell level correlation result in HBV+ samples
DIP2A expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).