HIV Target gene Detail Information

> DIDO1 Gene Search Result

Gene Information

Gene Name	DIDO1
Gene ID	11083
Gene Full Name	death inducer-obliterator 1
Gene Alias	BYE1; DIO1; DATF1; DIDO2; DIDO3; DIO-1; DATF-1; C20orf158; dJ885L7.8
Transcripts	ENSG00000101191
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;Vesicles;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q9BTC0
HGNC ID	HGNC:2680
VEGA ID	OTTHUMG00000032945
OMIM ID	604140
String ID	9606.ENSP00000266070
PharmGKB ID	PA27147

Target gene [DIDO1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003151	chr20	67	1		68	View
4003715	chr20	55		1	56	View
4004163	chr20	9	29	10	48	View
4004223	chr20	44	3		47	View
4006770	chr20	12	9	2	23	View
4007560	chr20	10	9		19	View
4007676	chr20	15	3		18	View
4011911	chr20	3	3		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DIDO1 expression and immune infiltrating cell level correlation result in HIV+ samples
DIDO1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DIDO1 expression and immune infiltrating cell level correlation result in HIV+ samples
DIDO1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).