HIV Target gene Detail Information

> DHX15 Gene Search Result

Gene Information

Gene Name	DHX15
Gene ID	1665
Gene Full Name	DEAH-box helicase 15
Gene Alias	DBP1; HRH2; DDX15; PRP43; PRPF43; PrPp43p
Transcripts	ENSG00000109606
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	O43143
HGNC ID	HGNC:2738
VEGA ID	OTTHUMG00000160304
OMIM ID	603403
String ID	9606.ENSP00000336741
PharmGKB ID	PA27204

Target gene [DHX15] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005231	chr4	31	4		35	View
4008999	chr4	11	2		13	View
4009579	chr4	4	7		11	View
4012995	chr4	4			4	View
4014044	chr4	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DHX15 expression and immune infiltrating cell level correlation result in HIV+ samples
DHX15 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DHX15 expression and immune infiltrating cell level correlation result in HIV+ samples
DHX15 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).