HTLV1 Target gene Detail Information

> DHRS4L1 Gene Search Result

Gene Information

Gene Name	DHRS4L1
Gene ID	728635
Gene Alias	SDR25C4
Transcripts	ENSG00000284807
Virus	HTLV1
Gene Type	ncRNA
HPA Location Info
HGNC ID	HGNC:19732
OMIM ID	615195
Drugbank ID	BE0003983
PharmGKB ID	PA134878665

Target gene [DHRS4L1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000354	chr14	1511	305	192	2008	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of DHRS4L1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
DHRS4L1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).