Home
Virus
Gene
Disease
Dataset
Download
Help
 
HBV Target gene Detail Information

> DHCR24 Gene Search Result


Gene Information
Gene Name DHCR24
Gene ID 1718
Gene Full Name 24-dehydrocholesterol reductase
Gene Alias DCE; SELADIN1; Nbla03646; seladin-1
Transcripts ENSG00000116133
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q15392
HGNC ID HGNC:2859
VEGA ID OTTHUMG00000009989
OMIM ID 606418
String ID 9606.ENSP00000360316
PharmGKB ID PA27320
Target gene [DHCR24] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005820 chr1 41 6 47 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of DHCR24 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
DHCR24 expression: Low -> High
Lollipop of DHCR24 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of DHCR24 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DHCR24 expression and immune infiltrating cell level correlation result in HBV+ samples
DHCR24 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).