HIV Target gene Detail Information

> DGKK Gene Search Result

Gene Information

Gene Name	DGKK
Gene ID	139189
Gene Full Name	diacylglycerol kinase kappa
Transcripts	ENSG00000274588
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q5KSL6
HGNC ID	HGNC:32395
VEGA ID	OTTHUMG00000021520
OMIM ID	300837
String ID	9606.ENSP00000477515
Drugbank ID	BE0010286; BE0009935
PharmGKB ID	PA142671978

Target gene [DGKK] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4015723	chrX		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DGKK expression and immune infiltrating cell level correlation result in HIV+ samples
DGKK expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).