HIV Target gene Detail Information

> DGKD Gene Search Result

Gene Information

Gene Name	DGKD
Gene ID	8527
Gene Full Name	diacylglycerol kinase delta
Gene Alias	dgkd-2; DGKdelta
Transcripts	ENSG00000280873
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q16760
HGNC ID	HGNC:2851
VEGA ID	OTTHUMG00000133290
OMIM ID	601826
String ID	9606.ENSP00000264057
Drugbank ID	BE0002297; BE0009935
PharmGKB ID	PA27312

Target gene [DGKD] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000453	chr2	41	215	198	454	View
4002982	chr2	72	1		73	View
4014430	chr2	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DGKD expression and immune infiltrating cell level correlation result in HIV+ samples
DGKD expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DGKD expression and immune infiltrating cell level correlation result in HIV+ samples
DGKD expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).