HBV Target gene Detail Information

> DGKB Gene Search Result


Gene Information
Gene Name DGKB
Gene ID 1607
Gene Full Name diacylglycerol kinase beta
Gene Alias DGK; DAGK2; DGK-BETA
Transcripts ENSG00000136267
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q9Y6T7
HGNC ID HGNC:2850
VEGA ID OTTHUMG00000152477
OMIM ID 604070
String ID 9606.ENSP00000385780
Drugbank ID BE0010289; BE0009935
PharmGKB ID PA27311
Target gene [DGKB] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1018164 chr7 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DGKB expression and immune infiltrating cell level correlation result in HBV+ samples
DGKB expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).