HIV Target gene Detail Information

> DGKA Gene Search Result

Gene Information

Gene Name	DGKA
Gene ID	1606
Gene Full Name	diacylglycerol kinase alpha
Gene Alias	DAGK; DAGK1; DGK-alpha
Transcripts	ENSG00000065357
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;Mitochondria;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	P23743
HGNC ID	HGNC:2849
VEGA ID	OTTHUMG00000170109
OMIM ID	125855
String ID	9606.ENSP00000328405
Drugbank ID	BE0002324; BE0009935
PharmGKB ID	PA27310

Target gene [DGKA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008573	chr12	14			14	View
4013577	chr12	2	1		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DGKA expression and immune infiltrating cell level correlation result in HIV+ samples
DGKA expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DGKA expression and immune infiltrating cell level correlation result in HIV+ samples
DGKA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).