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HBV Target gene Detail Information

> DGCR2 Gene Search Result


Gene Information
Gene Name DGCR2
Gene ID 9993
Gene Full Name DiGeorge syndrome critical region gene 2
Gene Alias IDD; LAN; DGS-C; SEZ-12
Transcripts ENSG00000070413
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins
Uniport_ID P98153
HGNC ID HGNC:2845
VEGA ID OTTHUMG00000150141
OMIM ID 600594
String ID 9606.ENSP00000263196
PharmGKB ID PA27307
Target gene [DGCR2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001487 chr22 291 322 55 668 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of DGCR2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
DGCR2 expression: Low -> High
Lollipop of DGCR2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of DGCR2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DGCR2 expression and immune infiltrating cell level correlation result in HBV+ samples
DGCR2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).