HIV Target gene Detail Information

> DGAT1 Gene Search Result

Gene Information

Gene Name	DGAT1
Gene ID	8694
Gene Full Name	diacylglycerol O-acyltransferase 1
Gene Alias	ARAT; DGAT; ARGP1; DIAR7
Transcripts	ENSG00000285482
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;Nucleoli;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins
Uniport_ID	O75907
HGNC ID	HGNC:2843
VEGA ID	OTTHUMG00000174606
OMIM ID	604900
String ID	9606.ENSP00000482264
PharmGKB ID	PA27303

Target gene [DGAT1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006849	chr8	12	3	7	22	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DGAT1 expression and immune infiltrating cell level correlation result in HIV+ samples
DGAT1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DGAT1 expression and immune infiltrating cell level correlation result in HIV+ samples
DGAT1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).