HIV Target gene Detail Information

> DERL2 Gene Search Result

Gene Information

Gene Name	DERL2
Gene ID	51009
Gene Full Name	derlin 2
Gene Alias	FLANa; F-LANa; CGI-101; F-LAN-1; derlin-2; DERtrin-2
Transcripts	ENSG00000072849
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9GZP9
HGNC ID	HGNC:17943
VEGA ID	OTTHUMG00000102040
OMIM ID	610304
String ID	9606.ENSP00000158771
PharmGKB ID	PA134896343

Target gene [DERL2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006990	chr17	21			21	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DERL2 expression and immune infiltrating cell level correlation result in HIV+ samples
DERL2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DERL2 expression and immune infiltrating cell level correlation result in HIV+ samples
DERL2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).