HIV Target gene Detail Information

> DENND6B Gene Search Result

Gene Information

Gene Name	DENND6B
Gene ID	414918
Gene Full Name	DENN domain containing 6B
Gene Alias	AFI1B; FAM116B
Transcripts	ENSG00000205593
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8NEG7
HGNC ID	HGNC:32690
VEGA ID	OTTHUMG00000150210
String ID	9606.ENSP00000391524
PharmGKB ID	PA144596432

Target gene [DENND6B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4013531	chr22	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DENND6B expression and immune infiltrating cell level correlation result in HIV+ samples
DENND6B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).