HBV Target gene Detail Information

> DENND5A Gene Search Result

Gene Information

Gene Name	DENND5A
Gene ID	23258
Gene Full Name	DENN domain containing 5A
Gene Alias	EIEE49; RAB6IP1
Transcripts	ENSG00000184014
Virus	HBV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q6IQ26
HGNC ID	HGNC:19344
VEGA ID	OTTHUMG00000165716
OMIM ID	617278
String ID	9606.ENSP00000328524
PharmGKB ID	PA164718737

Target gene [DENND5A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003879	chr11	56	45	3	104	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of DENND5A expression and immune infiltrating cell level correlation result in HBV+ samples
DENND5A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).