HTLV1 Target gene Detail Information

> DENND4B Gene Search Result

Gene Information

Gene Name	DENND4B
Gene ID	9909
Gene Full Name	DENN domain containing 4B
Gene Alias	KIAA0476
Transcripts	ENSG00000198837
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	O75064
HGNC ID	HGNC:29044
VEGA ID	OTTHUMG00000037157
String ID	9606.ENSP00000354597
PharmGKB ID	PA142671629

Target gene [DENND4B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6008763	chr1	34	6	2	42	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of DENND4B expression and immune infiltrating cell level correlation result in HTLV1+ samples
DENND4B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).