HBV Target gene Detail Information

> DENND1B Gene Search Result

Gene Information

Gene Name	DENND1B
Gene ID	163486
Gene Full Name	DENN domain containing 1B
Gene Alias	FAM31B; C1ORF18; C1orf218
Transcripts	ENSG00000213047
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Nuclear speckles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q6P3S1
HGNC ID	HGNC:28404
VEGA ID	OTTHUMG00000035653
OMIM ID	613292
String ID	9606.ENSP00000479816
PharmGKB ID	PA134951951

Target gene [DENND1B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1012158	chr1	2	2	3	7	View
1016482	chr1	1			1	View
1018350	chr1				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of DENND1B expression and immune infiltrating cell level correlation result in HBV+ samples
DENND1B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).