HBV Target gene Detail Information

> DEFB4A Gene Search Result


Gene Information
Gene Name DEFB4A
Gene ID 1673
Gene Full Name defensin beta 4A
Gene Alias BD-2; SAP1; DEFB2; DEFB4; HBD-2; DEFB-2; DEFB102
Transcripts ENSG00000171711
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted secreted proteins, Transporters
Uniport_ID O15263
HGNC ID HGNC:2767
VEGA ID OTTHUMG00000129314
OMIM ID 602215
String ID 9606.ENSP00000303532
PharmGKB ID PA27249
Target gene [DEFB4A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1401588 chr8 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DEFB4A expression and immune infiltrating cell level correlation result in HBV+ samples
DEFB4A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).